Brin is a 2010 fellow of the Institute for Ethics and Emerging Technologies. He helped establish the Arthur C. Clarke Center for Human Imagination (UCSD). He serves on the advisory board of NASA's Innovative and Advanced Concepts group and frequently does futurist consulting for corporations and government agencies.
Brin consults and speaks for a wide variety of groups interested in the future, ranging from Defense Department agencies and the CIA to Procter & Gamble, SAP, Google and other major corporations. He has also been a participant in discussions at the Philanthropy Roundtable and other groups seeking innovative problem solving approaches.
Brin has a very active side career in public speaking and consultation. He appears frequently on science or future related television shows such as The Universe, Life After People, Alien Encounters, Worlds of Tomorrow.
He also serves on the Board of Advisors for the Museum of Science Fiction.
Much of Brin's work outside the Uplift series focuses on the impact on human society of technology, a theme which commonly appears in contemporary North American science fiction. This is most noticeable in The Practice Effect, Glory Season and Kiln People.
Brin's Jewish heritage is the source of two other strong themes in his works. Tikkun Olam ("repairing the world", i.e. people have a duty to make the world a better place) is originally a religious concept, but Brin, like many non-orthodox Jews, has adapted this into a secular notion of working to improve the human condition, to increase knowledge, and to prevent long-term evils. Brin has confirmed that this notion in part underscores the notion of humans as "caretakers" of sentient-species-yet-to-be, as he explains in a concluding note at the end of Startide Rising; and it plays a key role in The Uplift War, where the Thennanin are converted from enemies to allies of the Terragens (humans and other sapients that originated on Earth) when they realize that making the world a better place and being good care-takers are core values of both civilizations. Many of Brin's novels emphasize another element of Jewish tradition, the importance of laws and legality, whether intergalactic law in the Uplift series or that of near-future California in Kiln People but, on the other hand, Brin has stated that "Truly mature citizens ought not to need an intricate wrapping of laws and regulations, in order to do what common sense dictates as good for all".
Additionally, Brin wrote two short stories set in the Uplift universe, "Temptation" and "Aficionado". "Temptation" appeared in Robert Silverberg's anthology Far Horizons: All New Tales from the Greatest Worlds of Science Fiction and is set after the events in the Infinity's Shore. "Aficionado" was published in the limited-edition collection Tomorrow Happens, and is a short-story prequel to the novels. This story was originally published as "Life in the Extreme" in Popular Science Magazine Special Edition (August 1998). Both stories are also freely available on Brin's website. Brin has stated that he intends to return to the Uplift universe at some point, but is not currently working on anything. A segment of his novel Existence deals with the origins of dolphin uplift and hence might be considered linked to the Uplift Universe.
Brin co-wrote with Kevin Lenagh Contacting Aliens: An Illustrated Guide to David Brin's Uplift Universe.