Get Noracymethadol essential facts below. View Videos or join the Noracymethadol discussion. Add Noracymethadol to your topic list for future reference or share this resource on social media.
Clinical data
ATC code
  • None
Legal status
Legal status
CAS Number
PubChem CID
ECHA InfoCard100.014.571 Edit this at Wikidata
Chemical and physical data
Molar mass339.471 g/mol g·mol-1
3D model (JSmol)

Noracymethadol (INN) is a synthetic opioid analgesic related to methadone that was never marketed.[1] In a clinical trial of postpartum patients it was reported to produce analgesia comparable to that of morphine but with less nausea, dizziness, and drowsiness.[2][3] Other side effects included salivation, ataxia, and respiratory depression that was reversible by naloxone.[2][3] Similarly to many of its analogues, noracymethadol is a Schedule I controlled substance in the United States with an ACSCN of 9633 and 2013 annual manufacturing quota of 12 grammes. [4] and is also controlled internationally under the United Nations Single Convention on Narcotic Drugs of 1961.[5] The salts known are the gluconate (free base conversion ratio 0.633) and hydrochloride (0.903).

Noracymethadol is an acetyl ester of methadol and it can be said with some precision that it is either the heroin or 6-monoacetylmorphine analogue of methadol, and being a methadol it exhibits optical isomerism. The other methadols (acetylmethadol, methadol &c) have at least four optical isomers (see Orlaam).

See also


  1. ^ F. Macdonald. Dictionary of Pharmacological Agents. CRC Press. p. 1447. ISBN 978-0-412-46630-4. Retrieved 2012.
  2. ^ a b Gruber C.M., Baptisti A. (1963). "Estimating the acceptability of morphine and noracymethadol in postpartum patients". Clinical Pharmacology and Therapeutics. 4: 172-81. doi:10.1002/cpt196342172. PMID 13950878.
  3. ^ a b Lister RE (June 1966). "The toxicity of some of the newer narcotic analgesics". The Journal of Pharmacy and Pharmacology. 18 (6): 364-83. doi:10.1111/j.2042-7158.1966.tb07890.x. PMID 4381372.
  4. ^ "Controlled Substances in Schedule I". Drug Enforcement Administration - Office of Diversion Control. Retrieved .
  5. ^ Thomas Nordegren (1 March 2002). The A-Z Encyclopedia of Alcohol and Drug Abuse. Universal-Publishers. p. 468. ISBN 978-1-58112-404-0. Retrieved 2012.

  This article uses material from the Wikipedia page available here. It is released under the Creative Commons Attribution-Share-Alike License 3.0.



Music Scenes