Apamea Myrlea (; Ancient Greek: ? ?) was an ancient city and bishopric (Apamea in Bithynia) on the Sea of Marmara, in Bithynia, Anatolia; its ruins are a few kilometers south of Mudanya, Bursa Province in the Marmara Region of Asian Turkey.
To distinguish this city from the many others called Apamea, the name Apamea Myrlea used here adds to the name (Apamea) it was given when rebuilt as an important city the name (Myrlea) it previously bore as a smaller town. It was also referred to as Apamea Myrl?on (Apamea of Myrlea).
The town was founded as a colony of the Colophonians and was called ? (Myrleia or Myrlea). Philip V of Macedon took the town, as it appears, during his war against the king of Pergamon, and gave it to his ally, King Prusias I of Bithynia, who fortified and enlarged it - indeed almost rebuilt it - around 202 BC, renaming it ? (transcribed as Apameia, Apamea, or Apamia), after his wife, Apama III.
The Romans made Apamea a colonia, apparently in the time of Augustus, or perhaps Julius Caesar, in view of the adjective "Iulia" that appear on its coins under Roman rule. Its earlier coins were stamped ? , but in Roman times they bore the label C.I.C.A. (= Colonia Iulia Concordia Apamea).
This Apamea in the Late Roman province of Bithynia became the seat of a Christian bishop in the 4th century and was at first a suffragan of Nicaea, but became an autocephalous archdiocese some time before the Fourth Council of Constantinople (Roman Catholic) in 869, at which its archbishop Paulus took part.
Since the Latin Catholic archdiocese was thus nominally restored (in ?1633), it has had the following archiepiscopal incumbents, but is vacant since decades :