Margaret of Blois (French: Marguerite; died 1230) was suo jure Countess of Blois from 1218 to 1230, in what is now France.
She was daughter of Theobald V of Blois and Alix of France.
Margaret married three times. Her first marriage was to Hugh of Oisy, Lord of Montmirail. Her second husband was Otto I, Count of Burgundy, with whom she had two daughters:
Finally, she married Walter II of Avesnes, they had: