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Karplus-Strong string synthesis is a method of physical modelling synthesis that loops a short waveform through a filtered delay line to simulate the sound of a hammered or plucked string or some types of percussion.
At first glance, this technique can be viewed as subtractive synthesis based on a feedback loop similar to that of a comb filter for z-transform analysis. However, it can also be viewed as the simplest class of wavetable-modification algorithms now known as digital waveguide synthesis, because the delay line acts to store one period of the signal.
Alexander Strong invented the algorithm, and Kevin Karplus did the first analysis of how it worked. Together they developed software and hardware implementations of the algorithm, including a custom VLSI chip. They named the algorithm "Digitar" synthesis, as a portmanteau for "digital guitar".
The fundamental frequency (specifically, the lowest nonzero resonant frequency) of the resulting signal is the lowest frequency at which the unwrapped phase response of the delay and filter in cascade is . The required phase delay D for a given fundamental frequency F0 is therefore calculated according to D = Fs/F0 where Fs is the sampling frequency.
The length of any digital delay line is a whole-number multiple of the sampling period. In order to obtain a fractional delay, interpolating filters are used with parameters selected to obtain an appropriate phase delay at the fundamental frequency. Either IIR or FIR filters may be used, but FIR have the advantage that transients are suppressed if the fractional delay is changed over time. The most elementary fractional delay is the linear interpolation between two samples (e.g., s(4.2) = 0.8s(4) + 0.2s(5)). If the phase delay varies with frequency, harmonics may be sharpened or flattened relative to the fundamental frequency. The original algorithm used equal weighting on two adjacent samples, as this can be achieved without multiplication hardware, allowing extremely cheap implementations.
Z-transform analysis can be used to get the pitches and decay times of the harmonics more precisely, as explained in the 1983 paper that introduced the algorithm.
A demonstration of the Karplus-Strong algorithm can be heard in the following Vorbis file. The algorithm used a loop gain of 0.98 with increasingly attenuating first order lowpass filters. The pitch of the note was A2, or 220 Hz.
Holding the period (= length of the delay line) constant produces vibrations similar to those of a string or bell. Increasing the period sharply after the transient input produces drum-like sounds.
Alex Strong and Kevin Karplus realized that the Karplus-Strong algorithm was physically analogous to a sampling of the transversal wave on a string instrument, with the filter in the feedback loop representing the total string losses over one period. Julius O. Smith III  and others generalized the algorithm to digital waveguide synthesis, which could also be used to model acoustic waves in tubes and on drum membranes. The first set of extensions and generalizations was presented in a paper in 1982 at the International Computer Music Conference in Venice, Italy, and published in more detail in 1983 in Computer Music Journal in an article entitled "Extensions of the Karplus Strong Plucked String Algorithm," by David A. Jaffe and Julius O. Smith.
The first musical use of the algorithm was in the work May All Your Children Be Acrobats written in 1981 by David A. Jaffe, and scored for eight guitars, mezzo-soprano and computer-generated stereo tape, with a text based on Carl Sandburg's The People, Yes. Jaffe continued to explore the musical and technical possibilities of the algorithm in Silicon Valley Breakdown, for computer-generated plucked strings (1982), as well as in later works such as Telegram to the President, 1984 for string quartet and tape, and Grass for female chorus and tape (1987).
The patent was licensed first to Mattel Electronics, which failed as a company before any product using the algorithm was developed, then to a startup company founded by some of the laid-off Mattel executives. They never got sufficient funding to finish development, and so never brought a product to market either. Eventually Yamaha licensed the patent, as part of the Sondius package of patents from Stanford. It is unknown whether any hardware using the algorithm was ever sold, though many software implementations (which did not pay any license fees to the inventors) have been released.
While they may not adhere strictly to the algorithm, many hardware components for modular systems have been commercially produced that invoke the basic principals of Karplus-Strong Synthesis: using an inverted, scaled control system for very small time values in a filtered delay line to create playable notes in the Western Tempered tuning system, controlled with volt per octave tracking or MIDI data. The Inventors were not specifically credited, though the term "Karplus-Strong Synthesis" is referenced in some of the manuals.
Hardware components capable of Karplus_Strong style synthesis are the Moog Clusterflux 108M, 4ms Company Dual Looping Delay, and 2HP Pluck.