John W. Drake
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John W. Drake

John W. Drake
CitizenshipUnited States of America
Alma materCaltech
Scientific career
Fieldsmutagenesis and DNA repair
Doctoral advisorRenato Dulbecco

John W. Drake is an American microbiologist, working for over half a century in the field of mutagenesis and DNA repair.

Education and early career

He completed an MS in Microbiology at the University of Illinois (with Paul M. Bingham). His interest in embryology led him to take his PhD at the California Institute of Technology in 1958[1] where he studied alongside Howard Temin in the laboratory of Renato Dulbecco.[2]

Research interests and career

John W. Drake, an early member of the Environmental Mutagen Society, chaired its "Committee 17" which published an influential position paper; "Environmental Mutagenic Hazards", in Science in 1975.[3] This described the research needs and regulatory responsibility for managing potential mutagenic compounds in the environment. It significantly influenced research direction, regulatory procedures and mutagenicity testing within industry within the United States and internationally.[4]

John W. Drake now heads the Spontaneous Mutation and DNA Repair Group within the Laboratory of Molecular Genetics at the National Institute of Environmental Health Sciences.[1]

Selected publications

  • Drake, John W. (2006). Cigna, Arrigo A.; Durante, Marco (eds.). "Mutation and DNA repair: from the Green Pamphlet to 2005". Radiation Risk Estimates in Normal and Emergency Situations. NATO Security through Science Series. Springer: 271-281. doi:10.1007/1-4020-4956-0_27. ISBN 978-1-4020-4955-2.
  • Drake, John W. (1958). Intracellular Interactions of Polioviruses: Interference and Multiplicity Reactivation (PDF) (Thesis). Caltech.


  1. ^ a b "Spontaneous Mutation & DNA Repair Group". NIEHS. Archived from the original on 20 December 2010. Retrieved 2010.
  2. ^ Drake, John W.; Crow, James F. (September 1996). "Recollections of HOWARD TEMIN (1934-1994)". Perspectives - Anecdotal, Historical and Critical Commentaries on Genetics. Genetics Society of America. 144 (1): 1-6. PMC 1207483. PMID 8878668.
  3. ^ "Environmental Mutagenic Hazards". Science. 187 (4176): 503-514. February 14, 1975. doi:10.1126/science.163482. PMID 163482.
  4. ^ "Environmental Mutagen Society web site". Archived from the original on April 16, 2011. Retrieved 2010.

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