Hydroxypethidine
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Hydroxypethidine
Hydroxypethidine
Hydroxypethidine.svg
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.738 Edit this at Wikidata
Chemical and physical data
FormulaC15H21NO3
Molar mass263.332 g/mol g·mol-1
3D model (JSmol)
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Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of the more commonly used pethidine (meperidine). Hydroxypethidine is significantly less potent than meperidine as an analgesic, (0.3x meperidine in potency) although it also has NMDA antagonist properties like its close relative ketobemidone.[1]

Hydroxypethidine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening.

Hydroxypethidine is under international control under the Single Convention on Narcotic Drugs 1961 and therefore controlled like morphine in most countries; in the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9627 and a 2014 annual aggregate manufacturing quota of 2 grammes. The salt in use is the hydrochloride, with a free base conversion ratio of 0.878. [2]

See also

References

  1. ^ Isbell Harris. The addiction liability of some analogues of meperidine. Journal of Pharmacology And Experimental Therapeutics, 1949; 97(2): 182-190
  2. ^ http://www.deadiversion.usdoj.gov/quotas/conv_factor/index.html



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Hydroxypethidine
 



 



 
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