Enterogastric Reflex
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Enterogastric Reflex

The enterogastric reflex is one of the three extrinsic reflexes of the gastrointestinal tract, the other two being the gastroileal reflex and the gastrocolic reflex.[1] The enterogastric reflex is stimulated by duodenal distension.[2] It can also be stimulated by a pH of 3-4 in the duodenum and by a pH of 1.5 in the stomach. Upon initiation of the reflex, the release of gastrin by G-cells in the antrum of the stomach is shut off. This in turn inhibits gastric motility and the secretion of gastric acid (HCl).[1]

Emptying inhibitory factors

The stomach's contents are inhibited from emptying into the small intestine by:

Emptying stimulatory factors

The stomach's contents empty through the pylorus, allowing digestion to proceed, when there is:


  1. ^ a b "Gastrointestinal Reflex Pathways". LibreTexts. Retrieved 2019.
  2. ^ a b "Enterogastric Reflex". Encyclopedia.com. Retrieved 2019.
  3. ^ "Vagal and splanchnic sensory pathways mediate inhibition of gastric motility induced by duodenal distension". American Journal of Physiology. Gastrointestinal and Liver Physiology. April 1992 – via Physiology.org.
  4. ^ "The slowing of gastric emptying by nine acids". The Journal of Physiology – via PubMed Central.
  5. ^ a b "Factors That Regulate Gastric Emptying". Physiology Plus. Retrieved 2019.
  6. ^ a b "Control of gastric emptying by osmolality of duodenal contents in man". Gastroenterology. 68: 1148. May 1975. PMID 1126594. Retrieved 2019.
  7. ^ "Nervous System of the Digestive System - Gastrointestinal Reflex Pathways". Boundless. Retrieved 2016.

  This article uses material from the Wikipedia page available here. It is released under the Creative Commons Attribution-Share-Alike License 3.0.



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