Reid wrote sexually explicit versions of hit songs for fun but only performed them for his friends at parties or in the studio. In 1971, he along with a band of studio musicians, recorded a whole album of these songs under the name Blowfly. The album, The Weird World of Blowfly, features Reid dressed as a low-rent supervillain on its cover. He created this alter ego to protect his career as a songwriter,[clarification needed] and continued to perform in bizarre costumes as his Blowfly character and continued to record sexually explicit albums throughout the 1970s and 1980s. The albums were widely popular as "party records". The explicit version of his song "Rapp Dirty" (a.k.a. "Blowfly's Rapp") helped the album Blowfly's Party reach No. 26 on Billboard Magazine's black albums chart and No. 82 on the Billboard Top 200 in 1980.
Blowfly's profane style earned Reid legal trouble. He was sued by songwriter Stanley Adams, who was ASCAP president at the time, for spoofing "What a Diff'rence a Day Makes" as "What a Difference a Lay Makes". Reid's own compositions have been sampled by dozens of hip hop, R&B, and electronic artists (such as Beyonce, Wu Tang Clan, DJ Quik, DMX, Method Man & Redman, Main Source, DJ Shadow, Eazy-E, RJD2, Jurassic 5, Big Daddy Kane, Mary J. Blige, Brand Nubian, and the Avalanches) but Reid received almost no money from sampling due to signing away most of his royalties.
Blowfly's Zodiac Blowfly LP (also released on CD in 1996 on Weird World Records)
includes the songs "If Eating You Is Wrong, I Don't
Want To Be Right", "The First Time Ever You Sucked My Dick", and
"Ain't No Head Like My Woman's Head", as well as a version of "Clean Up Woman",
which he co-wrote.
Another album of this period is The Weird World
of Blow Fly.
In 2003, Blowfly sold the rights to his entire catalog after years of debt. The catalog was said to be worth millions of unpaid royalties.
Blowfly's Punk Rock Party, a 2006 album release from Alternative Tentacles, features several punk rock classics given the Blowfly treatment--including a rewrite of the Dead Kennedys song "Holiday in Cambodia" recast as "R. Kelly in Cambodia", which features Biafra (the song's composer and original singer) playing a trial judge. The album also includes "I Wanna Be Fellated", "Gotta Keep Her Penetrated", "I Wanna Fuck Your Dog" and "Should I Fuck This Big Fat Ho?".
Blowfly completed his first tour of Australia in March 2007, and toured Germany with Die Ärzte in 2008. He performed at the 2010 Big Day Out music festival, held in Australia and New Zealand.
On January 12, 2016, Blowfly drummer "Uncle" Tom Bowker announced in a statement on the Blowfly Facebook page that Reid was suffering from terminal liver cancer and had been admitted to a hospice facility in Florida. According to Bowker, the singer would release his final LP - entitled 77 Rusty Trombones - in February 2016. Reid died on January 17, 2016, from cancer and multiple organ failure at the hospice facility in Lauderdale Lakes, Florida, aged 76.