Group E of the 2021 Africa Cup of Nations qualification tournament is one of the 12 groups that will decide the teams which qualify for the 2021 Africa Cup of Nations finals tournament. The group consist of four teams: Morocco, Mauritania, Central African Republic, and Burundi.
|1||Morocco||2||1||1||0||3||0||+3||4||Qualify for final tournament||—||0-0||23 Mar||8 Sep|
|2||Mauritania||2||1||1||0||2||0||+2||4||9 Jun||—||2-0||23 Mar|
|3||Central African Republic||2||1||0||1||2||2||0||3||31 Mar||8 Sep||—||2-0|
|4||Burundi||2||0||0||2||0||5||−5||0||0-3||31 Mar||9 Jun||—|
There were 8 goals scored in 4 matches, for an average of 2 goals per match (as of 19 November 2019).